Tag Archives: Swiss Institute for Experimental Cancer Research

A practical qPCR approach to detect TERRA, the elusive telomeric repeat-containing lncRNA

lncRNA

Telomeres, the heterochromatic structures that protect the ends of the chromosomes, are transcribed into a class of long non-coding RNAs, telomeric repeat-containing RNAs (TERRA), whose transcriptional regulation and functions are not well understood. The identification of TERRA adds a novel level of structural and functional complexity at telomeres, opening up a new field of research. TERRA molecules are expressed at ...

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