Commentary

Researchers develop new approach to study long non-coding RNAs

lncrna

New method identifies and determines role for newly discovered genetic units Until recently, scientific research concentrated almost exclusively on the 2 percent of the genome’s protein coding regions, virtually ignoring the other 98 percent – a vast universe of non-coding genetic material previously dismissed as ‘junk.’ In the past 10 years, scientists have discovered thousands of new long non-coding RNAs ...

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New lncRNA biomarkers for neuroblastoma

lncRNA

Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, and eventually also for treatment. “There is a need for new methods of treatment for high-risk patients, and that’s where our research can lead to ...

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Newly discovered lncRNA gene may protect against heart disease

lncRNA

UCLA-led study finds that so-called ‘selfish’ gene acts to remove cholesterol from blood vessels Scientists have identified a gene that may play a protective role in preventing heart disease. Their research revealed that the gene, called MeXis, acts within key cells inside clogged arteries to help remove excess cholesterol from blood vessels. Published in the journal Nature Medicine, the UCLA-led study ...

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