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Scientists image heart lncRNA structure for the first time

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Scientists at Los Alamos and international partners have created the first 3-D images of a special type of RNA molecule that is critical for stem cell programming and known as the “dark matter” of the genome. “As far as we know,” said corresponding author Karissa Sanbonmatsu, “this is the first full 3-D structural study of any long, non-coding RNA (lncRNA) ...

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A new approach to RNA sequencing reveals thousands of previously inaccessible lncRNA fragments in blood plasma

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New method opens unexplored realms for liquid biopsies A new approach to RNA sequencing reveals thousands of previously inaccessible RNA fragments in blood plasma that might serve as disease- and organ-specific biomarkers Advancing technology is allowing scientists increasingly to search for tiny signs of cancer and other health issues in samples of patients’ blood and urine. These “liquid biopsies” are ...

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A blood test for multiple sclerosis? Expect one in late May

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MedCityNews – The medical toolbox for treating multiple sclerosis (MS) has progressed in leaps and bounds over the last two decades, as highlighted by the recent approval of Ocrevus for the most severe and treatment-resistant form of the disease. Despite this success, the underlying disease mechanisms and triggers are not well understood. This makes diagnosis a challenge — with very high ...

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Call For Papers – Special Issue: Non-coding RNAs in Cancer

Editor: Aamir Ahmad, PhD, Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA Deadline: October 15th, 2016 Cancer is a deadly disease that affects millions of lives worldwide. The fight against cancer relies heavily on the availability of robust biomarkers for diagnosis, therapy and prognosis. In recent years, non-coding RNAs have attracted a lot of attention for their role in human cancers. The ...

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Biology student honored at international symposium in Italy for work on long non-coding RNAs

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Student’s poster on grapevine research places first Graduate biology student Zachary Harris won first place in the Bioinformatics, Big Data category at the International Symposium of Grapevine Physiology and Biotechnology in Verona, Italy. “We can think of the genome as the total genetic content of the organism. Embedded within that content is the instruction for making proteins,” said Harris. “Proteins ...

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New Research shows placental RNA may help protect embryo from viruses

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The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed. “What that means,” said Montserrat Anguera, an assistant professor in the University of Pennsylvania School of Veterinary Medicine, “is it has to make very specialized cells, it has to form structures to support ...

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Johns Hopkins student named NSF Graduate Research Fellow to Study Long Non-coding RNAs

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John’s Hopkins Hub – The National Science Foundation has selected 2,000 Graduate Research Fellows from across the country, including 18 current Johns Hopkins University students. The program recognizes and supports outstanding graduate students in science, technology, engineering, and mathematics disciplines who pursue research-based post-baccalaureate degrees at accredited institutions. The GRF is the oldest graduate fellowship of its kind and has ...

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Pathway Responsible For Breast Cancer Metastasis Identified By MD Anderson Researchers

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from Breast Cancer News Scientists at The University of Texas MD Anderson Cancer Center have discovered a signalling pathway responsible for breast cancer metastasis. The study, led by Liuqing Yang, Ph.D., assistant professor of molecular and cellular oncology, was published in this month’s issue of Cell.  Molecules called long non-coding RNAs (lncRNAs) are known because of their role in metastasis and tumor growth. However, until now, the dimensions ...

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Targeted Neuroblastoma Therapy One Step Closer

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from ScienceNetwork WA by  Anika Rodgers AUSTRALIAN researchers have uncovered new targets for therapy in the childhood cancer neuroblastoma. Histone Modification Group and Children’s Cancer Institute Australia for Medical Research’s Tao Liu says the researchers have been studying neuroblastoma in the hope of developing novel treatments. “Neuroblastoma is the most common solid tumour in early childhood and it accounts for ...

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