Tag Archives: University of Navarra

The multidimensional mechanisms of long noncoding RNA function


A major shift in our understanding of genome regulation has emerged recently. It is now apparent that the majority of cellular transcripts do not code for proteins, and many of them are long noncoding RNAs (lncRNAs). Increasingly, studies suggest that lncRNAs regulate gene expression through diverse mechanisms. Researchers from the University of Navarra review emerging mechanistic views of lncRNAs in gene ...

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Lnc-ing p53 and epigenetic silencing via a novel noncoding RNA

from Biome It is now well-established that noncoding regions of the genome have a vital role to play in gene expression. Genome-wide approaches have led to the identification of an abundance of noncoding RNAs, from microRNAs to long non-coding RNAs (lncRNAs). LncRNAs were initially discovered in the 1980’s but the extent of their transcription was only realized over twenty years ...

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