Tag Archives: University of Michigan

How Defeating THOR Could Bring a Hammer Down on Cancer

Researchers have identified and characterized a new type of RNA protein called THOR that plays a role in cancer development — and could serve as a target for drug development. It turns out Thor, the Norse god of thunder and the Marvel superhero, has special powers when it comes to cancer, too. Researchers at the University of Michigan Comprehensive Cancer ...

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PCAT14 is a Prognostic Biomarker in Prostate Cancer

lncRNA

Rapid advances in the discovery of long noncoding RNAs (lncRNAs) have identified lineage- and cancer-specific biomarkers that may be relevant in the clinical management of prostate cancer (PCa). Here University of Michigan researchers assembled and analyzed a large RNA-seq dataset, from 585 patient samples, including benign prostate tissue and both localized and metastatic PCa to discover and validate differentially expressed ...

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Analysis of long non-coding RNAs in the skin

lncRNA

Although analysis pipelines have been developed to use RNA-seq to identify long non-coding RNAs (lncRNAs), inference of their biological and pathological relevance remains a challenge. As a result, most transcriptome studies of autoimmune disease have only assessed protein-coding transcripts. Researchers from the University of Michigan used RNA-seq data from 99 lesional psoriatic, 27 uninvolved psoriatic, and 90 normal skin biopsies, ...

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Featured lncRNA Position – Postdoctoral research fellow

Employer: University of Michigan Posted: October 20, 2013 Expires: December 18, 2013 Requisition number: Science jobs from University of Michigan: We are seeking highly motivated postdoctoral fellows to conduct research on: (1) long noncoding RNA in glucose and lipid metabolism, and (2) mechanisms of small secreted proteins in metabolic crosstalk and disease. Successful candidates will perform basic biomedical research in ...

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