Tag Archives: type I collagen

Induction of long intergenic non-coding RNA HOTAIR in lung cancer cells by type I collagen


The tumor microenvironment is a crucial determinant in tumor progression. Interstitial extracellular matrix (ECM), such as type I collagen (Col-1), is aberrantly enriched in the tumor microenvironment and promotes tumor progression. Long intergenic non-coding RNAs (lincRNA) are a new family of regulatory RNAs that modulate fundamental cellular processes via diverse mechanisms. Researchers at Tulane University School of Medicine investigated whether ...

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