Tag Archives: Survival

Identification of four prognostic lncRNAs for survival prediction of patients with hepatocellular carcinoma

lncRNA

As the fifth most common cancer worldwide, Hepatocellular carcinoma (HCC) is also the third most common cause of cancer-related death in China. Several lncRNAs have been demonstrated to be associated with occurrence and prognosis of HCC. However, identification of prognostic lncRNA signature for HCC with expression profiling data has not been conducted yet. With the reuse of public available TCGA ...

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Panel of seven long noncoding RNA as a candidate prognostic biomarker for ovarian cancer

lncRNA

Ovarian cancer is one of the most common and lethal gynecological malignancies. The diagnosis of ovarian cancer is often at an advanced stage. Accumulated evidence suggests that long noncoding RNAs (lncRNAs) play important roles during ovarian tumorigenesis. In this study, using the lncRNA-mining approach, researchers from the Chinese Academy of Sciences and Fudan University analyzed lncRNA expression profiles of 493 ...

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The prognostic value of long noncoding RNAs in prostate cancer

lncRNA

The abnormally expressed LncRNAs played irreplaceable roles in the prognosis of prostate cancer (PCa). Therefore, researchers from Wuhan University conducted this systematic review and meta-analysis to summarize the association between the expression of LncRNAs, prognosis and clinicopathology of PCa. 18 eligible studies were recruited into their analysis, including 18 on prognosis and 9 on clinicopathological features. Results indicated that aberrant ...

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Seven LncRNA-mRNA based risk score predicts the survival of head and neck squamous cell carcinoma

lncrna

Dysregulation of mRNAs and long non-coding RNAs (lncRNAs) is one of the most important features of carcinogenesis and cancer development. However, studies integrating the expression of mRNAs and lncRNAs to predict the survival of head and neck squamous cell carcinoma (HNSC) are still limited, hitherto. In current work, researchers at the Zhejiang University School of medicine identified survival related mRNAs ...

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A panel of four-long noncoding RNA signatures predicts prostate cancer survival

lncRNA

Growing evidences showed that lncRNAs abnormally expressed in cancer tissues and played irreplaceable roles in tumorigenesis, progression and metastasis. In present study, researchers from Yangzhou University aimed to identify lncRNA expression signature that can predict biochemical recurrence-free (BCR-free) survival of prostate cancer (PCa) patients. A total of 291 patients with pathologic confirmed PCa in The Cancer Genome Atlas dataset were ...

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Three-lncRNA signature – a novel biomarker for the accurate prognosis prediction HNSCC

lncRNA

Long non-coding RNAs (lncRNAs) have important biological functions and can be used as prognostic biomarkers in cancer. To identify a lncRNA prognostic signature for head and neck squamous cell carcinoma (HNSCC). Researchers at the Shanghai Jiao Tong University School of Medicine analysed RNA-seq data derived from the TANRIC database to identify a lncRNA prognostic signature model using the orthogonal partial ...

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A long non-coding RNA signature to improve prognosis prediction of gastric cancer

lncRNA

Increasing evidence suggests long non-coding RNAs (lncRNAs) are frequently aberrantly expressed in cancers, however, few related lncRNA signatures have been established for prediction of cancer prognosis. Scientists at Shanghai JiaoTong University aimed at developing a lncRNA signature to improve prognosis prediction of gastric cancer (GC). Using a lncRNA-mining approach, they performed lncRNA expression profiling in large GC cohorts from Gene ...

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