Tag Archives: single nucleotide variants

ExInAtor – driver lncRNA discovery using mutational patterns in tumour DNA

lncRNA

Long noncoding RNAs (lncRNAs) represent a vast unexplored genetic space that may hold missing drivers of tumourigenesis, but few such “driver lncRNAs” are known. Until now, they have been discovered through changes in expression, leading to problems in distinguishing between causative roles and passenger effects. Researchers at the CRG – Barcelona Institute of Science and Technology have developed a different ...

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ExInAtor – driver lncRNA discovery using mutational patterns in tumour DNA

lncRNA

Long noncoding RNAs (lncRNAs) represent a vast unexplored genetic space that may hold missing drivers of tumourigenesis, but few such “driver lncRNAs” are known. Until now, they have been discovered through changes in expression, leading to problems in distinguishing between causative roles and passenger effects. Researchers at the Barcelona Institute of Science and Technology have developed a different approach for ...

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