Tag Archives: Shahid Beheshti University of Medical Sciences

The Role of Long Non Coding RNAs in the Repair of DNA Double Strand Breaks

lncRNA

DNA double strand breaks (DSBs) are abrasions caused in both strands of the DNA duplex following exposure to both exogenous and endogenous conditions. Such abrasions have deleterious effect in cells leading to genome rearrangements and cell death. A number of repair systems including homologous recombination (HR) and non-homologous end-joining (NHEJ) have been evolved to minimize the fatal effects of these ...

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