Tag Archives: SAMMSON

ExInAtor – driver lncRNA discovery using mutational patterns in tumour DNA

lncRNA

Long noncoding RNAs (lncRNAs) represent a vast unexplored genetic space that may hold missing drivers of tumourigenesis, but few such “driver lncRNAs” are known. Until now, they have been discovered through changes in expression, leading to problems in distinguishing between causative roles and passenger effects. Researchers at the CRG – Barcelona Institute of Science and Technology have developed a different ...

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lncRNAs Neat1 and SAMMSON: similar, yet different anti-cancer targets

lncRNA

A team of researchers led by Chris Marine (VIB-KU Leuven) has shown that NEAT1, a long non-coding RNA, plays an important role in the survival of highly dividing cells – cancer cells in particular. The research has a striking similarity to earlier findings by the Marine lab about SAMMSON, a long non-coding RNA gene on which the growth of aggressive ...

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