Tag Archives: Receiver operating characteristic

Panel of five lncRNAs provides a signature for the diagnosis and prognosis of gastric cancer

lncRNA

Gastric cancer (GC) is one of the most aggressive malignancies and has a poor prognosis. Identifying novel diagnostic and prognostic markers is of great importance for the management and treatment of GC. Long non-coding RNAs (lncRNAs), which are involved in multiple processes during the development and progression of cancer, may act as potential biomarkers of GC. Here, by performing data ...

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Transcriptome sequencing uncovers a three-long noncoding RNA signature in predicting breast cancer survival

lncRNA

Long noncoding RNAs (lncRNAs) play a crucial role in tumorigenesis. The aim of this study was to identify a lncRNA signature that can predict breast cancer patient survival. RNA expression data from 1064 patients were downloaded from The Cancer Genome Atlas project. Cox regression, Kaplan-Meier, and receiver operating characteristic (ROC) analyses were performed to construct a model for predicting the ...

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Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance

Long noncoding RNAs (lncRNAs) are newfound noncoding RNAs that are greater than 200 nucleotides in length. They have emerged recently as major players in governing fundamental biological processes. However, the expression level of lncRNAs and their clinical significances are not well understood. To investigate the lncRNA expression in gastric cancer, researchers at Ningbo University School of Medicine, China performed real-time ...

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