Tag Archives: RaNA Therapeutics

RaNA awarded first patent for blocking the interaction of long non-coding RNA with chromatin modifiers

lncRNA

CAMBRIDGE, Mass.–(BUSINESS WIRE)–RaNA Therapeutics, a leader in the discovery and development of a new class of medicines that target RNA, today announced that the United States Patent and Trademark office has issued the first patent covering RaNA’s transcriptional activation platform, U.S. Patent No. 9,328,346, titled “Polycomb-Associated Non-Coding RNAs.” This patent relates broadly to blocking the interaction of long non-coding RNA ...

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RaNA Therapeutics comes out of stealth, with new CEO, to further RNA targeting for diseases

lncRNA

from Beta Boston by Dennis Keohane RaNA Therapeutics, a company that is using a novel approach to fight disease using RNA, is coming out of stealth today and announcing that Ronald Renaud Jr. will be the company’s new chief executive officer. Founded at the end of 2011 using technology developed by Jeannie Lee, an investigator at the Howard Hughes Medical Institute ...

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RaNA Therapeutics Raises $20.7 Million to Harness the Potential of Long Non-coding RNA

CAMBRIDGE, Mass.–(BUSINESS WIRE)–RaNA Therapeutics, Inc. today announced it has completed a $20.7 million round of financing co-led by Atlas Venture, SR One, and Monsanto, with participation of Partners Innovation Fund. The company is developing a technology platform to enable selective activation of target genes and expression of therapeutic factors by targeting a type of regulatory RNA called long non-coding RNA. ...

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Targeting long non-coding RNA to therapeutically upregulate gene expression

lncRNA

The majority of currently available drugs and tool compounds exhibit an inhibitory mechanism of action and there is a relative lack of pharmaceutical agents that are capable of increasing the activity of effectors or pathways for therapeutic benefit. Indeed, the upregulation of many genes, including tumour suppressors, growth factors, transcription factors and genes that are deficient in various genetic diseases, ...

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