Tag Archives: Polymorphism

Secondary structure impacts patterns of selection in human lncRNAs

lncRNA

Metazoans transcribe many long non-coding RNAs (lncRNAs) that are poorly conserved and whose function remains unknown. This has raised the questions of what fraction of the predicted lncRNAs is actually functional, and whether selection can effectively constrain lncRNAs in species with small effective population sizes such as human populations. Here researchers from the Centre for Genomic Regulation (CRG) evaluate signatures ...

Read More »