Tag Archives: mutation drivers

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

lncRNA

Thousands of long non-coding RNAs (lncRNAs) lie interspersed with coding genes across the genome, and a small subset has been implicated as downstream effectors in oncogenic pathways. Here researchers from the University of Gothenburg make use of transcriptome and exome sequencing data from thousands of tumours across 19 cancer types, to identify lncRNAs that are induced or repressed in relation ...

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