Tag Archives: Multiple Myeloma

In Silico Characterization of miRNA and Long Non-Coding RNA Interplay in Multiple Myeloma

lncRNA

The identification of deregulated microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in multiple myeloma (MM) has progressively added a further level of complexity to MM biology. In addition, the cross-regulation between lncRNAs and miRNAs has begun to emerge, and theoretical and experimental studies have demonstrated the competing endogenous RNA (ceRNA) activity of lncRNAs as natural miRNA decoys in pathophysiological conditions, ...

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Investigation of Circulating LncRNAs in B-cell Neoplasms

Long non-coding RNAs (lncRNA) which are longer than 200 base pairs in length, play important role in the cellular machinery. Chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) are neoplasms of B-cells. Researchers at Istanbul University aimed to investigate circulating lncRNA levels of CLL and MM patients. For this purpose they selected 5 candidate lncRNAs (TUG1, LincRNA-p21, MALAT1, HOTAIR, and ...

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