Tag Archives: molecular switch

lncRNA IGS operates as a molecular switch that regulates the structure and function of the nucleolus.


The nucleolus is a plurifunctional organelle in which structure and function are intimately linked. Its structural plasticity has long been appreciated, particularly in response to transcriptional inhibition and other cellular stresses, though the mechanism and physiological relevance of these phenomena remain unclear. Using MCF-7 and other mammalian cell lines, researchers at the University of Ottawa, Canada describe a structural and ...

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