Exosomes are small (30-150 nm) vesicles of endosomal origin secreted by most cell types. Exosomes contain proteins, lipids, and RNA species including microRNA, mRNA, rRNA, and long noncoding
Read More »Detection of long non-coding RNAs in human breastmilk extracellular vesicles
Breastmilk has many documented beneficial effects on the developing human infant, but the components of breastmilk that influence these developmental pathways have not been fully elucidated. Increasing evidence suggests that non-coding RNAs encapsulated in extracellular vesicles (EVs) represent an important mechanism of communication between the mother and child. Long non-coding RNAs (lncRNAs) are of particular interest given their key role ...
Read More »Circulating long RNAs in serum extracellular vesicles: Their Characterization and Potential Application as Biomarkers for the Diagnosis of Colorectal Cancer
Long non-coding RNA and mRNAs are long RNAs (> 200 nucleotides) compared to microRNAs. In blood, long RNAs may be protected by serum extracellular vesicles, such as apoptotic bodies (ABs), microvesicles (MVs), and exosomes (EXOs). They are potential biomarkers for identifying cancer. Sera from 76 pre-operative CRC patients, 76 age- and sex-matched healthy subjects and 20 colorectal adenoma (CA) patients ...
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