Tag Archives: magnetic tweezers

Single molecule identification of homology-dependent interactions between long ssRNA and dsDNA


Long non-coding RNAs (lncRNAs) are prominently associated with chromosomes in an ever-increasing diversity of roles. To provide further insight into the potential nature of these associations, Harvard University researchers have explored, for the first time, the interaction of long single-stranded (ss) RNAs with cognate homologous double-stranded (ds) DNA in vitro Using magnetic tweezers, they measured the effects of ssRNA on ...

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