Tag Archives: liver disease

Acute liver failure is associated with altered cerebral expression profiles of long non-coding RNAs


Hepatic encephalopathy (HE) represents a serious complication of acute liver failure (ALF) in which cerebral edema leading to brainstem herniation as a result of increased intracranial hypertension is a major consequence. Long non-coding RNAs (lncRNAs) play a significant role in coordinating gene expression, with recent studies indicating an influence in the pathogenesis of several diseases. To investigate their involvement in ...

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Long non-coding RNA in liver diseases

The identification of the presence of large RNA transcripts that do not code proteins but that may have biological functions has provided an important new perspective in gene regulation. These long non-coding RNAs (lncRNAs) are being increasingly recognized to contribute to many biological processes through diverse mechanisms. The roles of these emerging genes are being recognized across kingdoms. These findings ...

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