Tag Archives: gapmers

Webinar on lncRNAs advancing therapeutics for cancer and heart disease

lncRNA

The authors of two new high impact papers in Nature and Science Translational Medicine describe how long non-coding RNAs are providing new therapeutic avenues in cancer and heart disease. Prof. Thomas Thum Director of the Institute of Molecular and Translational Therapeutic Strategies Hannover Medical School, Germany Prof. Thum will describe results from the recent Science Translational Medicine paper demonstrating that ...

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Webinar – lncRNA function and the use of Antisense LNA™ GapmeRs for knockdown of RNA

lncRNA

Watch our recent webinar and hear Dr. Zhen Xing from Liuqing Yang’s lab at MD Anderson Cancer Center present their work on long non-coding RNAs (lncRNA). In a recent Cell paper, they showed that knockdown of BCAR4 significantly reduced breast cancer metastasis in a mouse model. Hear about their approaches for the analysis of lncRNA function and get helpful tips. ...

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Long non-coding RNAs in the cardiovascular system

Dr. Stefanie Dimmeler – Dr. Reinier Boon – Katharina M. Michalik Katharina Michalik, Reinier Boon and Stefanie Dimmeler work at the Institute for Cardiovascular Regeneration at the Goethe University in Frankfurt, Germany. They are interested in microRNAs and long non-coding RNAs (lncRNAs) that control cardiovascular functions in endothelial cells. What is the background for your current project involving LNA™ GapmeRs? ...

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Exiqon launches advanced on-line tool for design of LNA gapmers for inhibition of mRNA and lncRNA

Exiqon A/S (NASDAQ OMX: EXQ), a leading supplier of high-value gene expression analysis products, today announced an extension to the LNA™ longRNA GapmeR product line with the launch of a novel on-line bioinformatics tool for the design of custom LNA™-gapmer antisense oligonucleotides for specific and efficient inhibition of mRNA and lncRNA. The new on-line LNA™ gapmer design tool allows scientists ...

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