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Tag Archives: CWRU

CWRU receives NIH funding to study lincRNAs in fight against colorectal cancer

September 27, 2018 Leave a comment 1,056 Views

lncRNA

Targeting long noncoding RNAs may offer gains compared to conventional approaches Certain genes that code for proteins have long been known to...

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Recent lncRNA Pubs

Long non-coding RNA activated by transforming growth factor beta alleviates lipopolysaccharide-induced inflammatory injury via regulating microRNA-223 in ATDC5 cells.
TFAP2C-Activated MALAT1 Modulates the Chemoresistance of Docetaxel-Resistant Lung Adenocarcinoma Cells.
Long non-coding RNA FGF13-AS1 inhibits glycolysis and stemness properties of breast cancer cells through FGF13-AS1/IGF2BPs/Myc feedback loop.
A novel long noncoding RNA regulates the immune response in MAC-T cells and contributes to bovine mastitis.
KLF5 and MYC modulated LINC00346 contributes to gastric cancer progression through acting as a competing endogeous RNA and indicates poor outcome.
Long noncoding RNA EGFR-AS1 promotes cell growth and metastasis via affecting HuR mediated mRNA stability of EGFR in renal cancer.
Long non-coding RNA ZNFX1-AS1 promotes the tumor progression and metastasis of colorectal cancer by acting as a competing endogenous RNA of miR-144 to regulate EZH2 expression.
Long non-coding RNA DNM3OS promotes tumor progression and EMT in gastric cancer by associating with Snail.

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What is lncRNA?

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs



PLoS ONE - Chakraborty, (2014)

Recent News

  • lncRNA

    Positions available – lncRNAs in vascular endothelial cells and smooth muscle cells

    24 days ago
  • lncRNA

    A lncRNA-mediated regulatory layer safeguarding embryonic cell fate transitions

    January 18, 2019
  • exosomes

    Exosomal lncRNAs and cancer: connecting the missing links

    January 18, 2019
  • lncRNA

    lncRNA SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4

    January 8, 2019
  • lncRNA

    lncRNAs as tools for cell line engineering in antibodies production

    December 1, 2018
  • lncRNA

    CisPi – a transcriptomic score for disclosing cis-acting disease-associated lincRNAs

    November 15, 2018

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