Tag Archives: COOLAIR

lncRNA COOLAIR displays a striking resemblance to an RNA molecular machine

lncRNA

Los Alamos-U.K. collaboration unveils hidden molecular machinery in RNA processes A special stretch of ribonucleic acid (RNA) called COOLAIR is revealing its inner structure and function to scientists, displaying a striking resemblance to an RNA molecular machine, territory previously understood to be limited to the cells’ protein factory (the ‘ribosome’) and not a skill set given to mere strings of ...

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Study unveils hidden molecular machinery in RNA processes

lncRNA

A special stretch of ribonucleic acid (RNA) called COOLAIR is revealing its inner structure and function to scientists, displaying a striking resemblance to an RNA molecular machine, territory previously understood to be limited to the cells’ protein factory (the ‘ribosome’) and not a skill set given to mere strings of RNA. “We are uncovering the nuts and bolts of plant ...

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Differential stabilization of R-loops – a new mechanism for regulation of gene expression

Science

Roles for long noncoding RNAs (lncRNAs) in gene expression are emerging, but regulation of the lncRNA itself is poorly understood. Now researchers at the John Innes Centre, UK have identified a homeodomain protein, AtNDX, that regulates COOLAIR, a set of antisense transcripts originating from the 3′ end of Arabidopsis FLOWERING LOCUS C (FLC). AtNDX associates with single-stranded DNA rather than ...

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