Tag Archives: Cleveland Clinic

Evolutionarily conserved long intergenic non-coding RNAs in the eye

lncRNA of the eye

The discovery that the mammalian transcriptome encodes thousands of long intergenic non-coding (linc) RNA transcripts, together with recent evidence that lincRNAs can regulate protein-coding genes, has added a new level of complexity to cellular transcriptional/translational regulation. Indeed several reports now link mutations in lincRNAs to heritable human disorders. Here researchers from the Cleveland Clinic identified a subset of lincRNAs in ...

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