Tag Archives: China

Community Curated Database For LncRNA


A wiki-style database hopes to serve as an online encyclopedia of lncRNA by and for the scientific community. Scientists have set up a long non-coding RNA (lncRNA) database aimed at harnessing the collective knowledge of the scientific community. This study has been published in Nucleic Acids Research. LncRNAs are RNAs that do not code for proteins but are nonetheless actively ...

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Systematic study of human long intergenic non-coding RNAs and their impact on cancer


The functional impact of several long intergenic non-coding RNAs (lincRNAs) has been characterized in previous studies. However, it is difficult to identify lincRNAs on a large-scale and to ascertain their functions or predict their structures in laboratory experiments because of the diversity, lack of knowledge and specificity of expression of lincRNAs. Furthermore, although there are a few well-characterized examples of ...

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Featured long non-coding RNA – LALR1

Wnt/β-Catenin signaling

Recently, long non-coding RNAs (lncRNAs) have been investigated as a new class of regulators of biological function. A recent study reported that lncRNAs control cell proliferation in hepatocellular carcinoma (HCC). However, the role of lncRNAs in liver regeneration and the overall mechanisms remain largely unknown. To address this issue, researchers at the Second Military Medical University, China carried out a ...

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Featured long non-coding RNA – PCGEM1

Prostate cancer (PCa) gene expression marker 1 (PCGEM1), a long noncoding RNA, has drawn increasing attention for its important role in PCa. However, the association between genetic variations in the PCGEM1 gene and risk of PCa has not been investigated yet. Researchers at Nanjing Medical University, China investigated the effect of two tagging single-nucleotide polymorphism (tSNPs; rs6434568 and rs16834898) in ...

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