Tag Archives: aging

Novel role for a lncRNA molecule found in the blood vessel wall may have implications for chronic vascular disease states and aging


Investigators from Brigham and Women’s Hospital have made a potentially exciting discovery by jumping into the abyss of the dark side of the genome. Once dismissed as “junk DNA,” roughly 75 percent of the human genome do not code for proteins. But these dark regions of the genome are far from junk — instead, they may hold tantalizing clues about ...

Read More »

Senescence-associated lncRNAs

Noncoding RNAs include small transcripts, such as microRNAs and piwi-interacting RNAs, and a wide range of long noncoding RNAs (lncRNAs). Although many lncRNAs have been identified, only a small number of lncRNAs have been characterized functionally. Here, researchers from the National Institute on Aging sought to identify lncRNAs differentially expressed during replicative senescence. They compared lncRNAs expressed in proliferating, early-passage, ...

Read More »