LncRNA, Cardiovascular development, Stem cells, Development, RNA biology, Regeneration
We are seeking a talented and highly motivated Postdoctoral Research Scientist with a strong background in development biology to study the role of lineage specific long non-coding RNAs (lncRNAs) in the context of embryonic cardiovascular development. We use differentiating human pluripotent stem cells as well zebrafish as model systems. Interfacing fundamental developmental biology, stem cell biology and translational research, the mission of the project is to gain deeper understanding to the function and molecular mechanisms of lineage specific lncRNAs in the context of human cardiovascular development and regeneration. The position will start no later than August 2014 for a period of 1-2 years, with the possibility to extend for additional 2 years. The position is available in the newly funded independent Research Group of Dr. Leo Kurian (PhD) http://www.lklab-uni-koeln.de/index.html
The group is affiliated to Department of Neurophysiology and Centre for Molecular Medicine (ZMMK), part of University of Cologne.
The group is funded by the North Rhine-Westphalia stem cell network. Qualified applicants should . Hold a Ph.D. in development biology . Proficient in zebrafish biology preferably in the context of cardiovascular development . Have a strong publication record in peer-reviewed journals . Willingness to learn differentiation systems based human pluripotent stem cells already established in the lab . Experience with TALEN or CRISPERi technologies will be advantageous . Possess the ability to conduct independent, high-quality, research in the biological sciences. Our lab and the institute in general are highly international and multicultural. Therefore it is not needed to learn German and our primary medium of communication is English. Our institute provides outstanding laboratory facilities and a highly supportive, interdisciplinary environment. Our postdocs also benefit from cutting edge core facilities including state of the art mass spectrometry core, microscopy core and genomics core as well as career development opportunities. The successful applicant will work in a team of young investigators and will also have the opportunity to supervise doctoral students, interns and medical students working in lab. Salary will be according to the German salary scale TV-L E13. Compensation includes health insurance and vacation time.
Applications should include . a brief statement of research interest . a brief outline of future perspective . a curriculum vitae . reprints of recent publications . the names/addresses of 2 references. Please use the following email address for correspondence firstname.lastname@example.org. University of Cologne is committed to diversity and is an Affirmative Action, Equal Opportunity Employer.
Our lab is located in Centre for Molecular medicine in Cologne (http://www.zmmk.uni-koeln.de/) and also affiliated to the department of Neurophysiology. The CMMC is a multidisciplinary centre affiliated to the University of Cologne bringing together physician scientists with basic researchers. The mission of the CMMC is to advance the understanding of the underlying molecular and cellular mechanisms of many common health problems. CMMC along with its partner institutes, the Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases (CECAD), the Cologne Center for Genomics and the Max-Planck Institute for Biology of Aging, are all located within the same campus, providing a vibrant, multidisciplinary and highly collaborative scientific environment. The CMMC is located in Cologne, the fourth-largest city in Germany and host of one of the oldest and largest universities in Europe. Cologne is one of the major German cultural hubs, with a vibrant, international and lively atmosphere housing ~60000 students. Located in the heart of Europe, Cologne is within driving distance of several major German and European cities and very close to several international airports.