PhD Position in Computational Biology of lncRNAs: Aachen, Germany

The Computational Biology Group of the Interdisciplinary Center for Clinical Research (IZKF) Aachen, RWTH Aachen University Hospital, Aachen, invites applicants for a PhD candidate in computational biology methods for modeling and detection of regulatory roles of long non-coding RNA during cell differentiation.The project is based on the development of computational methods to predict functional sites of long non-coding RNAs (lncRNA) from their sequence. In particular, we are interested in interaction of lncRNA with histone modifying proteins and DNA. Functional sites will be derived from the analysis of high-throughput methods such as RIP, CHART, CHIRP, and ChIP sequencing. This project will be performed in collaboration with stem cell specialists from the Institute for Biomedical Engineering, RWTH Aachen University.Applicants should hold a M.Sc. in Bioinformatics, Computer Science or related areas. Experience in the analysis of biological sequences and gene regulation is desirable. The candidate should have solid programming skills (C, Python and R) and acquaintance with Linux. Experience with high performance computing is a plus. The working language of the group is English.The position is based on the German TV-L 13 salary scale, including all German social benefits (health insurance and pension scheme). The expected starting date is March 2014. Interested candidates should send a brief statement of research interests, CV and the names of three references to jobs@costalab.org.The Computational Biology Group is supported by the Interdisciplinary Center for Clinical Research Aachen (IZKF) and hosted by the Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Hospital and the Helmholtz Institute for Biomedical Engineering, RWTH Aachen.