PhD Position Announcement

lncRNADoctoral student position with a doctoral grant in epigenetics, neural development and myelin Karolinska Institutet, Stockholm, Sweden Applications are invited for a doctoral student position in Epigenetic Mechanisms Regulating Oligodendrocyte Lineage in Development and Disease in Gonçalo Castelo-Branco´s group (

The PhD project, with the duration of 4 years, aims at identifying and characterizing the molecular mechanisms of action of key transcription factors, chromatin modifying-enzymes and non-coding RNAs, during oligodendrocyte linage progression during development and in disease models of multiple sclerosis. Technologies such as chromatin/RNA immunoprecipitation coupled with next generation sequencing, FACS, and quantitative proteomics will be used (see Castelo-Branco et al., Genome Biology 2013; Christophorou and Castelo-Branco et al., Nature 2014), along with other biochemistry, molecular and cell biology techniques.

We are looking for a highly motivated, driven, inquisitive, enthusiastic person interested in our area of research, and ready to explore new avenues in science. The candidate should have a collaborative approach to research, working productively in a team and contributing to a good social environment in the laboratory.

To qualify, the applicant must have previous research experience in other laboratories in biochemistry, molecular biology and/or cell biology techniques. Experience with techniques such as chromatin immunoprecipitation, protein/RNA biochemistry, microscopy and/or progenitor/stem cell culture is an advantage. Additional experience in bioinformatics and authorship(s) in scientific publications will be valued.

The application is to be submitted on the Karolinska Institutet NetRecruiter system (, until 2014-03-17.

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