from the RNA-Seq Blog
*Corresponding author: PV Nazarov
Genomics Research Unit, CRP-Sante, Luxembourg, Luxembourg
F1000Posters 2013, 4: 1446 (poster) [English] – Poster [1.22 MB]
Benelux Bioinformatics Conference 2013 , 9 – 10 Dec 2013, P82
Benelux Bioinformatics Conference
We compared two experimental approaches – standard microarray technology and next-generation RNA-seq for the analysis of changes in lncRNA expression profiles in NSCLC cancer tissue samples.
Generally speaking, RNA-seq technique outperforms arrays when studying lncRNAs. Cufflinks status should be taken into account together with counts or FPKM values in order to avoid misinterpreting the results.
Correlation between co-localized lncRNAs and mRNAs should be further investigated.
No relevant competing interests disclosed.
Luxembourg FNR CORE grant, ASTSTRO
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