lncRNA space could be twice as big as the miRNA space

from Genetic Engineering News by Enal Razvi, Ph.D.

Long Noncoding RNAs: Why You Need to Know about Them Now

lncRNA space could be twice as big as the miRNA space as they seem to have tremendous potential as disease biomarkers.

The focus of this GEN Market & Tech Analysis Report is to present some of our recent industry tracking of the long noncoding RNAs (lncRNAs) space as a follow-on to the GEN Report on microRNA Associations and Signatures.

In this report, we present the following:

  • Frame the position of lncRNAs vis-à-vis other classes of RNAs
  • Current breakout of the research marketplace as to which segments of research activity on lncRNAs are being focused upon
  • Publication analysis of the key lncRNAs across different disease classes

A key driver for the interest in lncRNAs is their sheer number in the genome (tens of thousands of lncRNAs are believed to exist) and the multitude of roles they are believed to play including structural roles, modulation/fine-tuning of gene expression in vivo, and epigenetic effects. Indeed, some lncRNAs have been associated with cancer and a few reports even suggest the possibility of lncRNAs with biomarker potential.

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