Press Release

Protein coding 'junk genes' may be linked to cancer

By using a new analysis method, researchers at Karolinska Institutet and Science for Life Laboratory (SciLifeLab) in Sweden have found close to one hundred novel human gene regions that code for proteins. A number of these regions are so-called pseudogenes, which may be linked to cancer. The expectation is now that this recently developed protein analysis method, published in the ...

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Biosearch Technologies Acquires Majority Stake in LightSpeed Genomics

Biosearch Technologies, Inc. (Biosearch) is a leading supplier of sophisticated oligonucleotide components to the rapidly growing molecular diagnostics industry. Biosearch has acquired a majority stake in LightSpeed Genomics, Inc. (LSG), a Santa Clara, California-based company developing an innovative optical detection solution for the life science and diagnostics industry based on its proprietary Synthetic Aperture Optics™ (SAO™) technology. Biosearch and LSG ...

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Garvan Institute receives grant to research role of long non-coding RNAs in Parkinson’s disease

lncrna

MEDIA RELEASE: 02 Oct 2013 The Michael J. Fox Foundation for Parkinson’s Research and Shake It Up Australia Foundation are co-funding a 12-month research project by Sydney’s Garvan Institute of Medical Research to look at the role of long non-coding RNAs in Parkinson’s disease. Long non-coding RNAs are complex molecules, produced from a DNA blueprint, that appear to play regulatory ...

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Exiqon launches advanced on-line tool for design of LNA gapmers for inhibition of mRNA and lncRNA

Exiqon A/S (NASDAQ OMX: EXQ), a leading supplier of high-value gene expression analysis products, today announced an extension to the LNA™ longRNA GapmeR product line with the launch of a novel on-line bioinformatics tool for the design of custom LNA™-gapmer antisense oligonucleotides for specific and efficient inhibition of mRNA and lncRNA. The new on-line LNA™ gapmer design tool allows scientists ...

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Scientists at Genome Institute of Singapore Discover Gene that Controls the Birth of Neurons

By ACN Newswire – August 27, 2013 10:36 PM EDT Discovery of long non-coding RNA’s role in neurogenesis may lead to cures for diseases such as Alzheimer’s disease Singapore, Aug 28, 2013 – (ACN Newswire) – Scientists at A*STAR’s Genome Institute of Singapore (GIS) have discovered an unusual gene that controls the generation of neurons[1]. This important finding, which is ...

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Targeting aggressive prostate cancer

Collaborative study shows how non-coding RNAs fuel cancer growth (SACRAMENTO, Calif.) — A team of researchers from UC Davis, UC San Diego and other institutions has identified a key mechanism behind aggressive prostate cancer. Published on August 14, 2013 in Nature, the study shows that two long non-coding RNAs (PRNCR1 and PCGEM1) activate androgen receptors, circumventing androgen-deprivation therapy. In their active state, ...

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CMU Prof receives Kaufman Grant for research on "High-Throughput Probing of Human IncRNA Structure"

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Press Release: Six Carnegie Mellon Professors Awarded Research Grants From Pittsburgh Foundation’s Charles E. Kaufman Fund Contacts: Ken Walters / 412-268-1151 / walters1@andrew.cmu.edu Chriss Swaney / 412-268-5776 / swaney@andrew.cmu.edu PITTSBURGH—Six Carnegie Mellon University professors are among the first series of grant recipients of The Charles E. Kaufman Foundation, part of The Pittsburgh Foundation, which today announced nearly $1.6 million in ...

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Exiqon launches LNA™ gapmers for inhibition of mRNA and lncRNA in functional studies

from Global Newswire Exiqon A/S (NASDAQ OMX: EXQ), a leading supplier of high-value gene expression analysis products, today announced the launch of its LNA™ longRNA GapmeR products for specific and efficient inhibition of mRNA and lncRNA. The LNA™ longRNA GapmeRs are high affinity antisense oligonucleotides used for functional analysis, allowing researches to study the gene function and downstream biological consequences ...

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Long non-coding RNAs act like enhancers of gene regulation

from The Max Planck Institute for Molecular Medicine The regulation of gene activity belongs to the most challenging questions of modern biology. So far, scientists know only a few mechanisms to switch single genes on or off. Now, an international team of scientists from the US, Germany, and Spain has described a new mode to regulate gene activity. In the ...

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'Activating' RNA takes DNA on a loop through time and space

Activating RNAs

from PhysOrg Long segments of RNA—encoded in our DNA but not translated into protein—are key to physically manipulating DNA in order to activate certain genes, say researchers at The Wistar Institute. These non-coding RNA-activators (ncRNA-a) have a crucial role in turning genes on and off during early embryonic development, researchers say, and have also been connected with diseases, including some ...

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