While scientists still don’t fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding...
Read More »Collaborative research sheds light on ‘dark’ portion of genome
Just as there is a mysterious dark matter that accounts for 85 percent of our universe, there is a “dark” portion of the human genome that has perplexed scientists for decades. A study published March 9, 2020, in Genome Research identifies new portions of the fruit fly genome that, until now, have been hidden in these dark, silent areas. The ...
Read More »Novel role for a lncRNA molecule found in the blood vessel wall may have implications for chronic vascular disease states and aging
Investigators from Brigham and Women’s Hospital have made a potentially exciting discovery by jumping into the abyss of the dark side of the genome. Once dismissed as “junk DNA,” roughly 75 percent of the human genome do not code for proteins. But these dark regions of the genome are far from junk — instead, they may hold tantalizing clues about ...
Read More »Phantom genes keep diabetes at bay
Unlike what we commonly refer to as 'genes', these phantom genes or 'Long noncoding RNA' (LncRNAs) do not lead to the production of proteins that our cells, and thus our entire bodies are made of...
Read More »lncRNA that suppresses melanoma tumors has been identified
A promising route to develop new treatments for skin cancer has been identified by University of Bath scientists, who have found a molecule that suppresses melanoma tumour growth. Although the research is at an early stage, the team hope that their work could help develop new ways to combat melanoma and potentially other cancers too. The team from the University ...
Read More »Grain traits traced to ‘dark matter’ of rice genome
Researchers from Washington University in St. Louis and the Chinese Academy of Agricultural Sciences discovered that rice domestication relied on selection for traits determined by a poorly understood portion of the rice genome...
Read More »Target lncRNA gene for esophageal squamous-cell cancer found
Korean researchers said they have found a new gene that controls the development of esophageal squamous cell carcinoma (ESCC), intractable cancer in the esophagus. The finding is likely to allow researchers to develop a diagnostic platform and a treatment agent for esophagus cancer. The research team, led by Professor Lee Sang-kil at Yonsei Institute of Gastroenterology at Yonsei University College ...
Read More »Researchers find new way to target childhood cancer
Australian-led international research effort has broken fresh ground in the race to find more effective treatments for the childhood cancer neuroblastoma, by uncovering a new and as-yet...
Read More »Scientists find lncRNA kill switch for HIV
Using genetic sequencing, University of California San Diego School of Medicine researchers have identified a principal cellular player controlling HIV reproduction in immune cells which, when turned...
Read More »Long non-coding RNA implicated in triple negative breast cancer
A slice of RNA that doesn’t code for a protein manages to stifle tumor-suppressing genes and wreck the cellular mechanism that flags cancer cells for destruction by the immune system. Writing this month in Nature Immunology, a team led by scientists at MD Anderson shows that the long, non-coding RNA (lncRNA) called LINK-A is a potential therapeutic target for triple negative breast ...
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