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Teenage drinking lnc’ed with epigenetic changes to emotional center of brain

lncrna

From Genetic Engineering News A study of human brain tissue has found that binge drinking during adolescence causes epigenetic changes that could be linked with the development of psychological problems and alcohol use disorder (AUD) in adulthood. The study, headed by researchers at the University of Illinois at Chicago (UIC) Center for Alcohol Research in Epigenetics, discovered that the brains ...

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Positions available – lncRNAs in vascular endothelial cells and smooth muscle cells

lncRNA

Positions are available for a post-doctoral fellow and established, non-tenure track Research Assistant/Associate Professor to study novel long non-coding RNAs (lncRNAs) in vascular endothelial cells and smooth muscle cells (see Pubmed IDs, 24578380, 27444199, 30584103, and 27856459). Candidates will work in a highly interactive, state-of-the-art Cardiovascular Research Institute using modern technology including next generation sequencing, biochemical assays for elucidating lncRNA function (eg, PAR-CLIP), and ...

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lncRNAs as tools for cell line engineering in antibodies production

lncRNA

Chinese hamster ovary cells are the main mammalian cell expression system currently used for the production of recombinant protein biopharmaceuticals. One of the key processes determining the achievable biomass of cells in the bioreactor and the yield and quality of recombinant protein from such systems is mRNA translation. Translation is the process by which ribosomes and associated cellular machinery decode an mRNA ...

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