BioMed Research International – Call for Papers – Bioinformatics of Noncoding RNAs

hindawiThe recent transcriptome-wide reannotation of human and other genomes has revealed a wealth of information on the transcriptional potential of the genome at single nucleotide resolution. Analyses have revealed that only a small proportion of these transcripts has the ability to encode for proteins. The majority of transcripts in human now encompass a class of nonprotein coding (noncoding RNAs). The noncoding RNA class has been majorly subdivided based on the size of the functional transcript into small and long noncoding RNAs, each class having distinct subtypes and functional correlates. Recently, studies have increasingly shown that noncoding RNAs play critical roles in a variety of important biological processes and therefore are also associated with a wide spectrum of diseases through a distinctly different set of mechanisms. Noncoding RNAs are increasingly also becoming one of the most important molecules studied in biology and medicine as biomarkers and drug targets for diseases. Bioinformatics, as one strategy, contributed significantly to the acceleration of biomedical research of noncoding RNAs, for example, miRNA discovery, miRNA target prediction, miRNA expression analysis, miRNA function analysis, miRNA-disease association study, miRNA network analysis, miRNA molecular evolution, lncRNA discovery, lncRNA molecular evolution, lncRNA function analysis, and lncRNA-disease association analysis, just to name a few.

Discovery of noncoding RNAs from genome-scale experimental datasets and integrative analysis of datasets have become the mainstay of noncoding RNA biology. In this special issue, we would focus on bioinformatics (database, tool, software, method, and knowledge discovery) of noncoding RNAs. The special issue will provide a platform to integrate the most recent development and ideas in the field. We call for original research articles and reviews on the following topics. Potential topics include, but are not limited to:

  • Discovery of noncoding genes
  • Function analysis and prediction of noncoding RNAs
  • Interaction partner identification of noncoding RNAs
  • Analysis of high-throughput data of noncoding RNAs
  • Network biology of noncoding RNAs
  • Analysis and prediction of associations of noncoding RNAs, diseases, or environmental factors (e.g., drugs)
  • Molecular evolution of noncoding RNAs
  • Genetics and epigenetics of noncoding RNAs (e.g., SNP analysis)
  • The regulation analysis of noncoding RNAs (e.g., in cis or in trans to target genes)Structure and motif study of noncoding RNA sequence

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at

Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

  • Manuscript DueFriday, 19 July 2013
  • First Round of ReviewsFriday, 11 October 2013
  • Publication DateFriday, 6 December 2013

Lead Guest Editor

  • Qinghua Cui, Health Science Center, Peking University, Beijing, China

Guest Editors

  • Edwin Wang, National Research Council Canada, Ottawa, Canada
  • Vinod Scaria, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, India
  • Guiying Yan, Institute of Mathematics, Chinese Academy of Sciences, Beijing, China
  • Yi Zhao, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China

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