Author Archives: lncRNA Administrator

Scientists link lncRNA leptin with obesity

lncrna

Obesity is a major public-health problem in the United States and around the world, with an estimated 650 million people suffering from the condition. One of the biggest challenges of this ever-worsening condition is figuring out why people become obese in the first place, and why some people are more vulnerable to obesity than others. Now, scientists at The Rockefeller ...

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Measures of co-expression for improved function prediction of long non-coding RNAs

lncrna

Almost 16,000 human long non-coding RNA (lncRNA) genes have been identified in the GENCODE project. However, the function of most of them remains to be discovered. The function of lncRNAs and other novel genes can be predicted by identifying significantly enriched annotation terms in already annotated genes that are co-expressed with the lncRNAs. However, such approaches are sensitive to the ...

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Teenage drinking lnc’ed with epigenetic changes to emotional center of brain

lncrna

From Genetic Engineering News A study of human brain tissue has found that binge drinking during adolescence causes epigenetic changes that could be linked with the development of psychological problems and alcohol use disorder (AUD) in adulthood. The study, headed by researchers at the University of Illinois at Chicago (UIC) Center for Alcohol Research in Epigenetics, discovered that the brains ...

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Positions available – lncRNAs in vascular endothelial cells and smooth muscle cells

lncRNA

Positions are available for a post-doctoral fellow and established, non-tenure track Research Assistant/Associate Professor to study novel long non-coding RNAs (lncRNAs) in vascular endothelial cells and smooth muscle cells (see Pubmed IDs, 24578380, 27444199, 30584103, and 27856459). Candidates will work in a highly interactive, state-of-the-art Cardiovascular Research Institute using modern technology including next generation sequencing, biochemical assays for elucidating lncRNA function (eg, PAR-CLIP), and ...

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