Monthly Archives: March 2018

HLPI-Ensemble – Prediction of human lncRNA-protein interactions based on ensemble strategy


LncRNA plays an important role in many biological and disease progression by binding to related proteins. However, the experimental methods for studying lncRNA-protein interactions are time-consuming and expensive. Although there are a few models designed to predict the interactions of ncRNA-protein, they all have some common drawbacks that limit their predictive performance. Researchers from Liaoning University present a model called HLPI-Ensemble designed ...

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Long noncoding RNAs in lipid metabolism


Noncoding RNAs have emerged as important regulators of cellular and systemic lipid metabolism. In particular, the enigmatic class of long noncoding RNAs have been shown to play multifaceted roles in controlling transcriptional and posttranscriptional gene regulation. Researchers from the New York University School of Medicine discuss recent advances, current challenges and future opportunities in understanding the roles of lncRNAs in ...

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