Monthly Archives: April 2015

Postdoc position available – Johns Hopkins University

lncRNA

Highly motivated postdoctoral candidates are invited to lead several new projects to address fundamental questions in Biology. Current directions in the lab include nucleic acid interactions with proteins and small molecules, and microRNA biology. The Johns Hopkins Medical Institutions provide a stimulating and collaborative environment for biomedical research. Our lab is affiliated with the Department of Biochemistry and Molecular Biology ...

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Featured lncRNA – DEANR1

lncRNA

Long non-coding RNAs (lncRNAs) regulate diverse biological processes, including cell lineage specification. Here, researchers from Harvard Medical School report transcriptome profiling of human endoderm and pancreatic cell lineages using purified cell populations. Analysis of the data sets allows us to identify hundreds of lncRNAs that exhibit differentiation-stage-specific expression patterns. As a first step in characterizing these lncRNAs, they focus on an ...

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Utilizing iPlant to Unearth Long Non-Coding RNAs

lncRNA

These clips are highlights taken from some iPlant session presentations at the International Plant and Animal Genome Meeting XXIII (January 2015, San Diego). iPlant users from across the US presented on how they have leveraged various iPlant resources to enable their research and educational goals. Importantly, everything they have done, you can do using iPlant. To learn more about the ...

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An Evolutionary Relic of the Genome Causes Cancer

BOSTON — Pseudogenes, a sub-class of long non-coding RNA (lncRNA) that developed from the genome’s 20,000 protein-coding genes but lost the ability to produce proteins, have long been considered nothing more than genomic “junk.” Yet the retention of these 20,000 mysterious remnants during evolution has suggested that they may in fact possess biological functions and contribute to the development of ...

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