Tag Archives: squamous-cell lung carcinomas

Featured long non-coding RNA – RNA-LET

RNA-LET

In this study, researchers from Second Military Medical University, China found that the lncRNA Low Expression in Tumor (lncRNA-LET) was generally downregulated in hepatocellular carcinomas, colorectal cancers, and squamous-cell lung carcinomas. They demonstrated that hypoxia-induced histone deacetylase 3 repressed lncRNA-LET by reducing the histone acetylation-mediated modulation of the lncRNA-LET promoter region. Interestingly, the downregulation of lncRNA-LET was found to be ...

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