Tag Archives: RATA

The lncRNA SLNCR1 Mediates Melanoma Invasion

lncRNA

 Increased expression of SLNCR1 is associated with reduced overall melanoma survival  SLNCR1 knockdown decreases melanoma invasion  The transcription factors AR and Brn3a bind adjacent sequences in SLNCR1  SLNCR1, AR, and Brn3a are all required for upregulating the matrix metalloproteinase MMP9 Long non-coding RNAs (lncRNAs) have been implicated in numerous physiological processes and diseases, most notably cancers. However, little is known ...

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