Tag Archives: cancer

Long Noncoding RNA in Cancer

lncrna

Long noncoding RNAs (lncRNAs), which are encoded by a vast less explored region of the human genome, may hold missing drivers of cancer and have gained attention recently as a potentially crucial...

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Decoding critical long non-coding RNA in ovarian cancer

lncrna

Ovarian cancer is the most lethal gynecologic malignancy in the United States, resulting in an estimated 14,100 deaths and 22,500 new cases in 2017 alone. This high mortality is primarily caused by resistance to therapy and the diagnosis of ovarian cancer after it has already metastasized, which occurs in approximately 80 percent of patients. A new study from Sidney Kimmel ...

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University of Newcastle lands $675K to study lncRNA

lncRNA

In total, the University of Newcastle (UON) has attracted $12.2m in the latest round of National Health and Medical Research Council (NHMRC) funding to investigate some of the nation’s and world’s greatest health challenges. Senior Deputy Vice-Chancellor (Research and Innovation), Professor Kevin Hall, said the NHMRC’s support for Newcastle’s researchers was testament to the University’s reputation for conducting world-class research. ...

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The Dark Side of the Epitranscriptome – Chemical Modifications in Long Non-Coding RNAs

lncrna

The broad application of next-generation sequencing technologies in conjunction with improved bioinformatics has helped to illuminate the complexity of the transcriptome, both in terms of quantity and variety. In humans, 70-90% of the genome is transcribed, but only ~2% carries the blueprint for proteins. Hence, there is a huge class of non-translated transcripts, called long non-coding RNAs (lncRNAs), which have ...

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