Tag Archives: Arraystar

The molecular mechanisms responsible for sepsis-induced endothelial dysfunction leading to an elevated risk of cardiovascular diseases remain undefined. Endotoxic or septic shock is a potentially lethal complication of systemic infection by Gram-negative bacteria. Lipopolysaccharide (LPS) is a critical glycolipid component of the outer wall of Gram-negative bacteria, and many of the sepsis-associated cellular signals by Gram-negative bacteria are attributed to ...

Despite there being over 35,000 different lncRNA sequences described little is known regarding their molecular-pathological role in cutaneous squamous cell carcinoma (cSCC). In a pilot study by researchers at Ruhr-University Bochum, lncRNA and mRNA expression profiles were determined in cSCC and control (n = 6) by an Arraystar human lncRNA Microarray. Kyoto Encyclopedia of Genes and Genomes pathway enrichment and ...

Arraystar is going to launch Arraystar Mouse LncRNA Expression Microarray V3.0! This array is designed for the global profiling of mouse long noncoding RNAs (LncRNAs). In order to detect LncRNAs comprehensively and reliably, we updated the repertoire of LncRNAs represented on the previous Microarray V2.0. The Arraystar Mouse LncRNA Expression Microarray V3.0 contains the following four important changes from V2.0: ...

Long noncoding RNAs (LncRNAs) are eukaryotic RNA molecules greater than 200 nucleotides in length that have no protein-coding capacity. Recently, LncRNAs have emerged as important factors in gene regulation. The inappropriate expression of some LncRNAs has been demonstrated to cause diseases such as liver cancer and Alzheimer’s. Ed Davis, Ph.D., Technical Support Specialist at Arraystar, Inc. discusses the biological and ...

Introduction Long non-coding RNAs (LncRNAs) are evolutionarily conserved, longer than 200nt, non-coding RNA molecules found in eukaryotes. Growing evidence suggests that LncRNAs have emerged as important regulators for diverse functions1.  LncRNAs are involved in a surprisingly wide variety of cellular functions, including epigenetic silencing, transcriptional regulation, RNA processing, and RNA modification2.  In addition,  LncRNAs have been associated with human diseases ...

Arraystar Inc., the industry leader in Long non-coding RNA (LncRNA) analysis, is excited to announce the launch of our version 3.0 LncRNA microarray. LncRNAs are similar to messenger RNAs, yet do not encode proteins. These intriguing transcripts have recently captured the imagination of scientists investigating the regulation and biomarker profiling of animal development and diseases, such as cancer and Alzheimer’s. ...