Drs. Liuqing Yang and Chunru Lin, from the Department of Molecular & Cellular Oncology at MD Anderson Cancer Center, are interested in the functional role of long non-coding RNAs (lncRNAs) in cancer and genetic disease. We have demonstrated the molecular mechanisms of long non-coding RNAs in a variety of signaling pathways, including those that regulate breast cancer metastasis and metabolic reprogramming (Cell 2014, NCB 2016). The laboratory has developed and modified a variety of technologies to study the mechanisms of long non-coding RNAs, including RNAscope, RNA pulldown, in vivo lncRNA knockdown using Locked Nucleic Acids, CRISPR/Cas9-mediated lncRNA editing/knockout mouse model, and TARGATT technology-mediated lncRNA knockin/transgenic mouse model. Our newest projects will study lncRNAs’ functional roles in the development of breast/pancreatic/lung cancer, and metabolic diseases using the above mentioned mouse models. Postdoc candidates should possess mastery of basic techniques in biochemistry, cell biology, immunology, and mouse genetics. Applicants should also be independent thinkers who are always willing to learn. The postdoc candidates should expect to join the lab in around three months. The salary will be based on the NIH postdoc salary scale.
• Use cutting-edge methods to seek novel cancer therapy targets in mouse or human cells
• Be responsible for the design and execution of experimental work, data analysis and their written records
• Attend and present at internal and international meetings
• Be expected to publish data in top scientific journals
• PhD in Molecular Biology, Biochemistry or related field
• Outstanding publication record
• Strong previous experience in biochemistry
• Prior experience in RNA biology is preferred.
• Some programming and bioinformatic skills is preferred.
• Excellent communication with a focus on teamwork is required.
Please send a letter of intent, curriculum vitae, names and addresses of three to five references, and a brief summary of past research accomplishments and future research plans to:
Chunru Lin, PhD, Assistant Professor
The University of Texas MD Anderson Cancer Center
Department of Lymphoma/Myeloma
1515 Holcombe Blvd, Unit 0429
Houston, TX 77030-4009
MD Anderson Cancer Center is an equal opportunity employer and does not discriminate on the basis of race, color, religion, age, national origin, sex, sexual orientation, gender identity/expression, disability, veteran status, genetic information, or any other basis protected by federal, state, or local laws, unless such distinction is required by law. All positions at The University of Texas MD Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.…