The advent of high-throughput genome scale technologies has enabled us to unravel a large amount of the previously unknown transcriptionally active regions of the genome. Recent genome-wide studies have provided annotations of a large repertoire of various classes of noncoding transcripts. Long noncoding RNAs (lncRNAs) form a major proportion of these novel annotated noncoding transcripts, and presently known to be involved in a number of functionally distinct biological processes. Over 18 000 transcripts are presently annotated as lncRNA, and encompass previously annotated classes of noncoding transcripts including large intergenic noncoding RNA, antisense RNA and processed pseudogenes. There is a significant gap in the resources providing a stable annotation, cross-referencing and biologically relevant information. lncRNome has been developed by researchers at the CSIR Institute of Genomics and Integrative Biology, India with the aim of filling this gap by integrating annotations on a wide variety of biologically significant information into a comprehensive knowledgebase.
Database URL: http://genome.igib.res.in/lncRNome.
- Bhartiya D, Pal K, Ghosh S, Kapoor S, Jalali S, Panwar B, Jain S, Sati S, Sengupta S, Sachidanandan C, Raghava GP, Sivasubbu S, Scaria V. (2013) lncRNome: a comprehensive knowledgebase of human long noncoding RNAs. Database (Oxford)2013(0), bat034. [article]