Industry News

IQuity lands $150K NIH grant for autoimmune disease research

exosomes

Nashville-based IQuity — which analyzes RNA data to develop tools that help physicians diagnose autoimmune diseases — has received a $150,000 grant from the National Institutes of Health’s Small Business Innovation Research program. The grant will help fund IQuity’s ongoing research into long non-coding RNAs and their usefulness in distinguishing fibromyalgia from rheumatic diseases including rheumatoid arthritis and lupus, according ...

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RaNA awarded first patent for blocking the interaction of long non-coding RNA with chromatin modifiers

lncRNA

CAMBRIDGE, Mass.–(BUSINESS WIRE)–RaNA Therapeutics, a leader in the discovery and development of a new class of medicines that target RNA, today announced that the United States Patent and Trademark office has issued the first patent covering RaNA’s transcriptional activation platform, U.S. Patent No. 9,328,346, titled “Polycomb-Associated Non-Coding RNAs.” This patent relates broadly to blocking the interaction of long non-coding RNA ...

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RaNA Therapeutics comes out of stealth, with new CEO, to further RNA targeting for diseases

lncRNA

from Beta Boston by Dennis Keohane RaNA Therapeutics, a company that is using a novel approach to fight disease using RNA, is coming out of stealth today and announcing that Ronald Renaud Jr. will be the company’s new chief executive officer. Founded at the end of 2011 using technology developed by Jeannie Lee, an investigator at the Howard Hughes Medical Institute ...

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lncRNA Market Trends – Learn the latest about the expanding and evolving long noncoding RNA space.

lncRNA

from Genetic Engineering News by Enal Razvi, Ph.D. The focus of this GEN Market & Tech Analysis report is to present some of our recent industry tracking of the long noncoding RNA (lncRNA) space, as this space is expanding and evolving.Highlights of this report: The lncRNA space is expanding and the numbers of lncRNA sequences deposited in the biological databases ...

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RaNA Therapeutics Raises $20.7 Million to Harness the Potential of Long Non-coding RNA

CAMBRIDGE, Mass.–(BUSINESS WIRE)–RaNA Therapeutics, Inc. today announced it has completed a $20.7 million round of financing co-led by Atlas Venture, SR One, and Monsanto, with participation of Partners Innovation Fund. The company is developing a technology platform to enable selective activation of target genes and expression of therapeutic factors by targeting a type of regulatory RNA called long non-coding RNA. ...

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lncRNAs and Epigenetic Modulations: Potential Hotspots

lncRNA

from Genetic Engineering News Market and Technology Analysis The focus of this GEN Market & Tech Analysis report is to present a snapshot of regional epigenetic down- and up-regulation in cancer with a focus toward prostate cancer. We present here long-range epigenetic silencing (LRES) as a means for downregulation of stretches of the genome as well as long-range epigenetic activation ...

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RNAi Screens and the Reagents That Enable Them

from Genetic Engineering News 2013 (Vol. 33, No. 19) by Jeanene Swanson RNAi screens for functional genomics typically look for loss- or gain-of-function phenotypes. They currently have many applications, including target discovery and validation, lead identification and optimization, mechanism of action discovery, predictive toxicology, and biomarker identification. While reagents are gaining ground, technical difficulties remain in how best to perform ...

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Biosearch Technologies Acquires Majority Stake in LightSpeed Genomics

Biosearch Technologies, Inc. (Biosearch) is a leading supplier of sophisticated oligonucleotide components to the rapidly growing molecular diagnostics industry. Biosearch has acquired a majority stake in LightSpeed Genomics, Inc. (LSG), a Santa Clara, California-based company developing an innovative optical detection solution for the life science and diagnostics industry based on its proprietary Synthetic Aperture Optics™ (SAO™) technology. Biosearch and LSG ...

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lncRNA space could be twice as big as the miRNA space

lncRNA

from Genetic Engineering News by Enal Razvi, Ph.D. Long Noncoding RNAs: Why You Need to Know about Them Now lncRNA space could be twice as big as the miRNA space as they seem to have tremendous potential as disease biomarkers. The focus of this GEN Market & Tech Analysis Report is to present some of our recent industry tracking of ...

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Exiqon launches advanced on-line tool for design of LNA gapmers for inhibition of mRNA and lncRNA

Exiqon A/S (NASDAQ OMX: EXQ), a leading supplier of high-value gene expression analysis products, today announced an extension to the LNA™ longRNA GapmeR product line with the launch of a novel on-line bioinformatics tool for the design of custom LNA™-gapmer antisense oligonucleotides for specific and efficient inhibition of mRNA and lncRNA. The new on-line LNA™ gapmer design tool allows scientists ...

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