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Scientists discover lncRNA that could revert cellular ageing

lncrna

Researchers at Instituto de Medicina Molecular (iMM) João Lobo Antunes have found that manipulating a single RNA molecule is enough to revert cellular ageing. Throughout time all cells age gradually, contributing to the development of several diseases. Inducing cellular regeneration is one of the strategies used to fight diseases associated with cellular ageing. However, aged cells tend to be highly ...

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Identification of transposable elements contributing to tissue-specific expression of long non-coding RNAs

lncrna

It has been recently suggested that transposable elements (TEs) are re-used as functional elements of long non-coding RNAs (lncRNAs). This is supported by some examples such as the human endogenous retrovirus subfamily H (HERVH) elements contained within lncRNAs and expressed specifically in human embryonic stem cells (hESCs), as required to maintain hESC identity. There are at least two unanswered questions ...

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